Lenti-Trop2 CAR (scFv-28BBζ)-VP(VP-CAR-LC669)

The ready-to-use lentiviral particles of Lenti-Trop2 CAR (scFv-28BBζ)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv-CD28-41BB-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.


Specifications


Type of Therapeutics
Chimeric Antigen Receptor
Target
Trop2
Expression Cassette
scFv-CD28-41BB-CD3ζ
Promotor
CMV
Packaging System
Lentivirus
Packaging Cell
293T
Targeting Diseases
Ovarian cancer, Melanoma

Target


Introduction
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.
Alternative Names
TACSTD2; tumor-associated calcium signal transducer 2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
Gene ID

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products


Carcinoma

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
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Tel: 44-207-048-3343

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