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Anti-VSV8 T cell receptor (N15), pCDTCR1 (TCR-C258Z)

The vector of anti-VSV8 T cell receptor (TCR) is constructed for the engineering of T cell to target VSIV VSV8. The T cells are genetically modified through transduction with a lentiviral vector expressing VSV8-specific T cell receptor. And the vector product was designed for the treatment of VSV Infection.

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Details

  • Target
  • VSV8
  • Target Species
  • VSIV
  • Epitope
  • RGYVYQGL
  • Format
  • Non-modified
  • HLA
  • H-2Kb
  • Targeting Diseases
  • VSV Infection
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Antibody Clone
  • N15
  • Antibody Host
  • Mouse

Target

  • Official Symbol
  • VSV8
  • Introduction
  • This octapeptide is amino acids 52 to 59 fragment of the the vesicular stomatitis virus (VSV) nucleoprotein. VSV-8 is derived from the VSV nucleoprotein that is expressed in the cytosol of the infected cells. CTL response against VSV in H-2Kb mice is directed against this single VSV-8 immunodominant peptide. This peptide forms complex with murine MHC class I molecule H-2Kb, which is similar to human HLA class I.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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