The vector of anti-CEA chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CEA. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CEA antibody linked to FcεRIγ signaling domains. And the vector product was designed for the treatment of colon carcinoma.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-MZ145||Anti-CEA (F11-39) h(41BB-CD3ζ) CAR, pCDCAR1|
|CAR-T-2-M314-CZ||Anti-CEA scFv h(b2c-CD3ζ) CART, pCDCAR1|
|CAR-MZ144||Anti-CEA (F11-39) h(CD28-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC798||Lenti-CEA CAR (scFv-CD28-OX40-CD3ζ, SCA431) Viral Particle|
|CAR-MZ108||Anti-CEA (MFE23) h(CD28-41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC147||Lenti-CEA CAR (scFv-CD3ζ, BW431/26) Viral Particle|
|CAR-LC375||Anti-CEACAM5 h(CD28-CD3ζ, GITR) Armoured CAR, pCDCAR1|
|CAR-T-2-M314-4Z||Anti-CEA scFv h(CD4-CD3ζ) CART, pCDCAR1|
|CAR-MZ105||Anti-CEA (MFE23) h(CD3ζ) CAR, pCDCAR1|
|CAR-T-2-M314-BZ||Anti-CEA scFv h(41BB-CD3ζ) CART, pCDCAR1|
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