The vector of anti-CEA chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CEA. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CEA antibody linked to CD8 hinge-transmembrane domain and CD3-zeta signaling domains. And the vector product was designed for the treatment of colon carcinoma.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-MZ145||Anti-CEA (F11-39) h(41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC797||Lenti-CEA CAR (scFv-OX40-CD3ζ, SCA431) Viral Particle|
|VP-CAR-LC153||Lenti-CEA CAR (scFv-41BB-CD3ζ, BW431/26) Viral Particle|
|CAR-T-2-M314-BZ||Anti-CEA scFv h(41BB-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC152||Lenti-CEA CAR (scFv-CD8-CD3ζ, BW431/26) Viral Particle|
|VP-CAR-LC151||Lenti-CEA CAR (scFv-CD4-CD3ζ, BW431/26) Viral Particle|
|CAR-T-3-M314-2BZ||Anti-CEA scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1|
|VP-TCR-C036||Lenti-CEA T cell receptor (Affinity enhanced) Viral Particle|
|VP-CAR-LC147||Lenti-CEA CAR (scFv-CD3ζ, BW431/26) Viral Particle|
|CAR-MZ106||Anti-CEA (MFE23) h(CD28-CD3ζ) CAR, pCDCAR1|
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