The vector of anti-ErbB2 (HER2) chimeric antigen receptor(CAR) is constructed for the engineering of NK cell to target human ErbB2. The NK cell is genetically modified through transduction with a lentiviral vector expressing scFv of anti-ErbB2 antibody linked to CD4 transmembrane domain and FcεRIγ signaling domains. And the vector product was designed for the treatment of breast carcinomas, ovarian carcinoma .
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|TCR-L231||Human anti-Her2 T cell receptor (H5), pCDTCR1|
|CAR-NK-2-M331-2Z||Anti-ErbB2 scFv h(CD28-CD3ζ) CARNK, pCDCAR1|
|VP-CAR-LC757||Lenti-ErbB2 CAR (scFv-CD28-CD3ζ, C6.5G98A) Viral Particle|
|VP-CAR-LC228||Lenti-ErbB2 CAR (scFv-CD8-CD3ζ, OTI5C4) Viral Particle|
|TCR-C100Z||Murinized anti-HER2 T cell receptor (HER2-4), pCDTCR1|
|TCR-L050Z||Human anti-HER2 (aa368-377) T cell receptor, pCDTCR1|
|VP-CAR-LC754||Lenti-ErbB2 CAR (scFv-CD28-CD3ζ, C6MH3-B1) Viral Particle|
|CAR-T-2-L337-8Z||Anti-ErbB2 scFv h(CD8-CD3ζ) CART, pCDCAR1|
|CAR-T-2-L337-4G||Anti-ErbB2 scFv h(CD4-FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC667||Lenti-HER2 CAR (scFv-CD28-41BB-CD3ζ) Viral Particle|
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