The vector of anti-ITGB3 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human ITGB3. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-ITGB3 antibody linked to CD3-zeta signaling domains. And the vector product was designed for the treatment of chronic lymphoid leukemia.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-T-2-L339-2G||Anti-ITGB3 scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC303||Lenti-ITGB3 CAR (scFv-CD28-41BB-CD3ζ, PM6/13) Viral Particle|
|VP-CAR-LC295||Lenti-ITGB3 CAR (scFv-CD3ζ, PM6/13) Viral Particle|
|VP-CAR-LC302||Lenti-ITGB3 CAR (scFv-b2c-CD3ζ, PM6/13) Viral Particle|
|VP-CAR-LC301||Lenti-ITGB3 CAR (scFv-41BB-CD3ζ, PM6/13) Viral Particle|
|VP-CAR-LC299||Lenti-ITGB3 CAR (scFv-CD4-CD3ζ, PM6/13) Viral Particle|
|CAR-T-2-L339-CZ||Anti-ITGB3 scFv h(b2c-CD3ζ) CART, pCDCAR1|
|CAR-T-2-L339-BZ||Anti-ITGB3 scFv h(41BB-CD3ζ) CART, pCDCAR1|
|CAR-T-1-L339-G||Anti-ITGB3 scFv h(FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC300||Lenti-ITGB3 CAR (scFv-CD8-CD3ζ, PM6/13) Viral Particle|
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