The vector of anti-MART-1(DMF5) chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human MART-1(DMF5). The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-MART-1(DMF5) antibody linked to CD28 transmembrane domain/ endodomain and CD3-zeta signaling domains. And the vector product was designed for the treatment of metastatic melanoma.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|TCR-L127||Human anti-MART-1 T cell receptor (S5-4), pCDTCR1|
|TCR-C139Z||Human anti-MART1 T cell receptor (SIG35α), pCDTCR1|
|VP-CAR-LC331||Lenti-MART-1(DMF5) CAR (scFv-CD3ζ, Melan-A) Viral Particle|
|VP-CAR-LC338||Lenti-MART-1(DMF5) CAR (scFv-b2c-CD3ζ, Melan-A) Viral Particle|
|CAR-T-2-M310-BZ||Anti-MART-1(DMF5) scFv h(41BB-CD3ζ) CART, pCDCAR1|
|CAR-T-2-M310-4G||Anti-MART-1(DMF5) scFv h(CD4-FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC332||Lenti-MART-1(DMF5) CAR (scFv-CD28-FcεRIγ, Melan-A) Viral Particle|
|VP-TCR-C298||Lenti-MART-1 (ELAGIGILTV) T cell receptor (DMF5) Viral Particle|
|VP-CAR-LC340||Lenti-MART-1(DMF5) CAR (scFv-CD28-OX40-CD3ζ, Melan-A) Viral Particle|
|TCR-C137Z||Human anti-MART1 T cell receptor (F5), pCDTCR1|
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