Close

COL18A1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple helix domains (collagenous domains) interrupted by non collagenous domains. A long isoform of the protein has an N terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.
  • CAR Vector Products

  • TCR Vector Products

  • TCR Cell Products

Loading...
  • Target Species:
  • Receptor Construction:
  • Vector Type:
  • Targeting Cell Type:
CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP449 COL18A1 (GPC1 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human COL18A1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP450 COL18A1 (ITGA5 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human COL18A1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP451 COL18A1 (ITGB1 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human COL18A1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1849 COL18A1 (GPC1 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human COL18A1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1850 COL18A1 (ITGA5 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human COL18A1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1851 COL18A1 (ITGB1 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human COL18A1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
Unable to find the desired product? Explore the Filter Options at the top of the list.
Key Updates
Newsletter NEWSLETTER

The latest newsletter to introduce the latest breaking information, our site updates, field and other scientific news, important events, and insights from industry leaders

LEARN MORE NEWSLETTER
New Solution NEW SOLUTION

CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.

LEARN MORE SOLUTION
NOVEL SOLUTION NOVEL TECHNOLOGY

Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.

LEARN MORE NOVEL TECHNOLOGY
NEW TECHNOLOGY NEW SOLUTION

Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.

LEARN MORE SOLUTION
Receive our latest news and insights.