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KRAS

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Diseases associated with KRAS include Ras-Associated Autoimmune Leukoproliferative Disorder and Noonan Syndrome 3. Among its related pathways are Arrhythmogenic right ventricular cardiomyopathy (ARVC) and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ1456 Anti-KRAS (8BA14) h(41BB-CD3ζ) CAR, pCDCAR1 Human 8BA14 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1457 Anti-KRAS (8BA15) h(41BB-CD3ζ) CAR, pCDCAR1 Human 8BA15 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4880 Anti-KRAS (8BA14) h(CD28-CD3ζ) CAR, pCDCAR1 Human 8BA14 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4881 Anti-KRAS (8BA15) h(CD28-CD3ζ) CAR, pCDCAR1 Human 8BA15 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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