ActivatorPep™ CytoStim, human-S (CA-LX031)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

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Product Name
ActivatorPep™ CytoStim, human-S

Cat. No.
CA-LX031

Product Summary
Creative Biolabs provides an extensive cell activation reagents including Expansion Kits and Activator peptides for global custom, which are suitable to many applications, such as in vitro stimulation antigen-specific cells. CytoStim has been developed for rapid and efficient restimulation of human effector/memory T cells. Which can be used for restimulation of human effector/memory T cells.

Background Information
CytoStim is an antibody-based reagent that acts similarly to a superantigen but independently of certain Vβ domains of the T cell receptor (TCR). It causes activation of T cells by binding to the TCR and crosslinking it to an MHC molecule of an antigen-presenting cell. Upon stimulation with CytoStim, CD4+ and CD8+ T cells start to secrete cytokines or up-regulate activation markers on their cell surface within a few hours. CytoStim is suitable for rapid stimulation of CD4+ and CD8+ T cells in fresh peripheral blood mononuclear cells (PBMCs), whole blood, or other leukocyte-containing single-cell suspensions from tissues. It can be used instead of SEB as a positive control in antigen-specific T cell stimulation assays or intracellular cytokine staining experiments to detect cytokine or activation marker expression.

Applications
Stimulation Reagents

Cross-reactivity
No significant cross-reactivity was observed among analytes in this panel.

Species Reactivity
Human

Purity or Quality Grade
Research Grade

Downstream Application
Pulsing of antigen-presenting cells for research;
Detection and analysis of antigen-specific CD4+ and CD8+ effector/memory T cells in PBMCs;

Product Size
for 1×108 total cells

Shipping Condition
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage Conditions
Store at -20°C.

Shelf life
> 6 Months from date of receipt under proper storage condition.

Product Use Statement
For research use only, not for diagnostic or therapeutic use.

Product Features
Efficient expansion and increased survival rate of Ag-specific T cells;
Provides a gentle activation stimulus that maintains high viability of activated and expanded T cells;

Research Category
Immunology

Panel Type
Stimulation for CD4+ and CD8+ T cells

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

ActivatorPep™ CytoStim, human-S (CA-LX031)

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