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Anti-GMM T cell receptor (Clone 42), pCDTCR1 (TCR-YC0493)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The vector of anti-GMM T cell receptor (TCR) is constructed for the engineering of T cell to target Glucose monomycolate restricted by human CD1b. The T cells are genetically modified through transduction with a lentiviral vector expressing GMM-specific T cell receptor.

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Details

  • Target
  • GMM
  • Epitope
  • Glucose monomycolate
  • Format
  • Non-Modified TCR
  • Allele
  • human CD1b
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~ 8 kb
  • Vector Type
  • Lentiviral vector
  • TCR Clone
  • clone 42
  • Host Species
  • Human

Target

  • Introduction
  • Mycolic acid and glucose monomycolate antigens possess the same kinds of mycolyl groups, yet function differently in activation of T cells. T cell response to GMM absolutely requires the glucose head group, including the indicated hydroxyl groups at positions C2 and C4.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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