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Anti-SEC24A T cell receptor (JA6), pCDTCR1 (TCR-YC1085)

The vector of anti-SEC24A T cell receptor (TCR) is constructed for the engineering of T cell to target SEC24A P469L (FLYNLLTRV) restricted by HLA-A2. The T cells are genetically modified through transduction with a lentiviral vector expressing SEC24A-specific T cell receptor.

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Details

  • Target
  • SEC24A
  • Epitope
  • FLYNLLTRV
  • Format
  • Non-Modified TCR
  • HLA
  • HLA-A2
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~ 8 kb
  • Vector Type
  • Lentiviral vector
  • TCR Clone
  • JA6
  • Host Species
  • Human

Target

  • Introduction
  • TMEM48 F169L, SEC24A P469L, and EXOC8 Q656P represent dominant antigens as T cell immunity was detected prior to vaccination (naturally occurring) and these neoantigens are processed and presented from endogenously expressed protein.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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