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Biotinylated Human CD19 CAR Detection Reagent, Fc Tag (CARD-LX012)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Evaluating CAR expression is an essential step in the production of CAR-T cells. Creative biolabs provides several detection reagents which are uniquely suitable for evaluation of CAR expression. Biotinylated Human CD19 CAR Detection Reagent, Fc Tag is a special detection reagent which carries a human IgG1 Fc fragment at the C-terminus, and is used to detect human CD19 CAR related to the study of Acute leukemia, B-Cell lymphoma.

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Specifications

  • Target
  • CD19
  • Application
  • ELISA, FC
  • Purity
  • >90%
  • Endotoxin Level
  • Less than 1.0 EU per μg by the LAL method.
  • Storage
  • For long term storage, the product should be stored at lyophilized state at -22°C or lower.
    Please avoid repeated freeze-thaw cycles.
  • Application Notes
  • The optimal working dilutions should be determined by the end user.
  • Diseases
  • Acute leukemia, B-Cell lymphoma
  • Molecular Characterization
  • It contains AA Pro 20 - Lys 291 (Accession # P15391-1). It is the biotinylated form of Human CD19, Fc Tag.
  • Conjugation
  • Biotin
  • Tag
  • Fc Tag
  • Size
  • 0.2 mg
  • Formulation
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
  • Expression
  • Human HEK293 cells
  • Host Species
  • Human
  • Species Reactivity
  • Human
  • Form
  • Lyophilized
  • Images
  • Figure 1 Structure

Target

  • Target Introduction
  • B-lymphocyte antigen CD19 is also known as CD19 (Cluster of Differentiation 19), is a single-pass type I membrane protein which contains two Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells.
  • Target Alternative Names
  • CD19 Molecule
  • Entrez Gene ID
  • 930

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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