The vector of anti-Carbonic anhydrase IX (CAIX) chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human Carbonic anhydrase IX (CAIX). The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-Carbonic anhydrase IX (CAIX) antibody linked to CD28 and OX40 and CD3ζ signaling domains. And the vector product was designed for the treatment of Clear cell renal cell carcinoma (ccRCC).
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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