CAR-specific Monoclonal Antibody Development to Detect CAR Expression

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

With unrivaled expertise and experience in antibody discovery and development, Creative Biolabs has developed an advanced platform to develop the CAR specific monoclonal antibodies. The CAR-specific antibody will help to detect the CAR expression during CAR in vitro assays. Our scientists are dedicated to comprehensive services for our one-stop CAR-T cell development.

Background

Immunotherapies have achieved unparalleled success in recent years, especially the chimeric antigen receptor (CAR) T therapy. According to the data in ClinicalTrial.gov, more than 600 CAR-T cell therapy programs are under clinical trials. During CAR-T cell therapy discovery, CAR detection is needed in the following stages.

CAR In Vitro Expression Test

For CAR engineered T cells or other cell types, CAR expression needs to be confirmed.

CAR In Vivo Distribution Test

After CAR-T cell infusion in animal models, bio-distribution of CAR-T cell needs to be tested.

CAR Distribution Test in Clinical Trial

Since CAR-positive T cell is related to anti-tumor activity, CAR expression and percentage of CAR-positive T cells after CAR-T cell infusion are critical.

CAR-specific Monoclonal Antibody Development to Detect CAR Expression

To facilitate CAR detection in all stages during CAR-T cell therapy discovery and development, Creative Biolabs has developed a specialized team to develop CAR-specific anti-idiotypic monoclonal antibodies. We are committed to developing anti-CAR mAbs with high sensitivity and high specificity. All anti-CAR mAbs will be validated before delivery to ensure high performance. Here are some featured CARs under frequent investigation. Our services cover the following CARs, but not limited to these. If you have any specific requirements, please just reach out to our team for an exclusive conversation.

For Hematologic Tumors
Anti-CD19 CARs	Anti-CD20 CARs	Anti-CD22 CARs	Anti-CD23 CARs	Anti-CD30 CARs
Anti-CD33 CARs	Anti-CD38 CARs	Anti-CD70 CARs	Anti-CD123 CARs	Anti-CD44v6 CARs
Anti-BCMA CARs	Anti-CD138 CARs	Anti-ROR CARs	Anti-NY-ESO-1 CARs	Anti-FAP CARs
Anti-NKG2D CARs	Anti-FLT3 CARs	Anti-CLL1 CARs	Anti-Lewis Y CARs	etc.
For Solid Tumors
Anti-CEA CARs	Anti-CD133 CARs	Anti-c-Met CARs	Anti-EGFR CARs	Anti-EPCAM CARs
Anti-GD2 CARs	Anti-FRα CARs	Anti-GPC3 CARs	Anti-GUCY2C CARs	Anti-HER2 CARs
Anti-ICAM-1 CARs	Anti-IL13Rα2 CARs	Anti-IL11Rα CARs	Anti-KRAS CARs	Anti-MAGE CARs
Anti-MUC1 CARs	Anti-PSCA CARs	Anti-CSPG CARs	Anti-IL-13R CARs	Anti-MSLN CARs
Anti-VEGFR CARs	Anti-PSMA CARs	Anti-WT1 CARs	Anti-CD24 CARs	etc.
We can offer CAR-specific antibody development services for various kinds of CARs, please reach out to us for further communication.

CAR-specific monoclonal antibody to detect CAR expression

Highlight Features

Precision: With extensive experiences in antibody development, our scientists are committed to providing the monoclonal antibodies that meet or exceed your specifications.
Accuracy: With our expertise and advanced platforms, we are confident in CAR-specific antibody development at high speed and efficiency.
Flexibility: Our team has extensive CAR experiences including every step during our one-stop CAR solutions. No matter you need the antibody development service only, or the one-stop CAR solution, we are ready for support.
Customization: We offer CAR-specific antibody development for all kinds of CARs.

With our skilled and advanced antibody development platforms, Creative Biolabs is confident to be the best option for our clients. If you need monoclonal antibody to detect the CAR, let's get the conversation started for your requests. Please feel free to contact us and our scientists will offer the best assistance at the earliest convenience.