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CellRapeutics™ Leukopak from Age-related Macular Degeneration Donor (XS-0426-XU224)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This Leukopak provides a highly concentrated collection of peripheral blood mononuclear cells from donors diagnosed with Age-related Macular Degeneration. The cellular composition includes systemic myeloid and lymphoid subsets involved in the chronic, low-grade inflammatory processes that contribute to retinal pigment epithelium damage. It serves as an expansive reservoir of primary cells for investigating the systemic innate-immune components of ocular neurodegeneration.

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from Age-related Macular Degeneration Donor
  • Cat. No.
  • XS-0426-XU224
  • Donor Age
  • Senior
  • Donor Health
  • Donors exhibit a chronic systemic pro-inflammatory state. The leukocyte profile is characterized by alterations in complement-regulating monocytic subsets and signatures associated with advanced age and senescent immune remodeling.
  • Ethnicity
  • Predominantly Caucasian.
  • Anticoagulant
  • Acid Citrate Dextrose, formulated to stabilize aged immune cell populations and minimize oxidative stress during collection.
  • Additional Donor Information
  • Each lot features a Leukopak from donors with dry or wet AMD. Profiles include visual impairment severity and age-matched clinical data to study the systemic myeloid contribution to retinal inflammation.
  • Clinical Profile
  • Disease stage and classification.

Additional Information

  • Medication History
  • Available upon request. Documentation of AREDS vitamins/supplements and history of anti-VEGF intravitreal injections, confirms absence of systemic immunomodulatory treatments.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from Age-related Macular Degeneration Donor, Leukopak, Age-related Macular Degeneration

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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