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CellRapeutics™ Leukopak from CIDP Donor (XS-0426-XU274)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Sourced from donors with Chronic Inflammatory Demyelinating Polyneuropathy, this Leukopak provides a specialized pool of cells involved in peripheral nerve demyelination. The leucocyte population is characterized by dysregulated T-cell and B-cell responses targeting myelin-associated glycoproteins. This product is critical for research into the pathogenesis of chronic autoimmune neuropathies and the discovery of circulating biomarkers for treatment response in CIDP.

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from CIDP Donor
  • Cat. No.
  • XS-0426-XU274
  • Donor Age
  • Middle-Aged, Senior
  • Donor Health
  • Diagnosed with Chronic Inflammatory Demyelinating Polyneuropathy. The leukocyte profile reflects a sustained immune-mediated attack on peripheral nerves, featuring specific pro-inflammatory T-cell and macrophage signatures.
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • Acid Citrate Dextrose, prioritized to maintain the viability of myelin-reactive T cells and peripheral nerve-homing lymphocytes.
  • Additional Donor Information
  • Each lot features a Leukopak from donors with Chronic Inflammatory Demyelinating Polyneuropathy. Profiles include neurological disability scores and history of intravenous immunoglobulin or plasma exchange therapy.
  • Clinical Profile
  • Disease course, electrodiagnostic findings, and history of IVIG, plasma exchange, or corticosteroid treatments.

Additional Information

  • Medication History
  • Available upon request. Records of intravenous immunoglobulin, corticosteroids, and history of plasma exchange or immunosuppressive maintenance.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from CIDP Donor, Leukopak, CIDP

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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