CellRapeutics™ Leukopak from Cirrhosis Donor (XS-0426-XU275)

Name: CellRapeutics™ Leukopak from Cirrhosis Donor
SKU: XS-0426-XU275
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This Leukopak is collected from donors with established Liver Cirrhosis, capturing the systemic immune dysfunction syndrome characteristic of end-stage liver disease. The cellular profile reflects a complex balance of chronic activation and functional exhaustion, including altered TLR-mediated signaling in monocytes and impaired T-cell effector functions. It is an essential resource for studying the systemic consequences of portal hypertension and the immunological basis of increased infection susceptibility in cirrhotic patients.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Cirrhosis Donor

Cat. No.
XS-0426-XU275

Donor Age
Middle-Aged, Senior

Donor Health
Clinically confirmed liver Cirrhosis. Leukocytes reflect a complex state of "cirrhosis-associated immune dysfunction", featuring both chronic inflammatory activation and elements of immune paralysis.

Ethnicity
Diverse backgrounds available.

Anticoagulant
Heparin, formulated to handle altered coagulation profiles and preserve the integrity of liver-homing immune cells.

Additional Donor Information
Each lot features a Leukopak from donors with clinically confirmed liver cirrhosis. Profiles specify the etiology and Child-Pugh score, providing a large cell volume for studying systemic immune exhaustion in end-stage liver disease.

Clinical Profile
Etiology, Child-Pugh score or MELD score, and documentation of portal hypertension or compensatory status.

Additional Information

Medication History
Available upon request. Documentation of diuretics, lactulose, antiviral medications, and management for portal hypertension complications.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Cirrhosis Donor, Leukopak, Cirrhosis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.