CellRapeutics™ Leukopak from Crohn's Disease Donor (XS-0426-XU235)

Name: CellRapeutics™ Leukopak from Crohn's Disease Donor
SKU: XS-0426-XU235
Rating: 5 (1 reviews)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Obtained from donors with biopsy-confirmed Crohn's Disease, this Leukopak offers a high-density population of immune cells involved in transmural intestinal inflammation. The specimen reflects the systemic expansion of Th17 cells and dysregulated innate lymphoid cells typical of this IBD phenotype. It serves as an expansive reservoir for studying leukocyte trafficking to the gastrointestinal tract and the discovery of novel therapeutic targets for granulomatous inflammation.

Specific Inquiry

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Donor Information

Product Name
CellRapeutics™ Leukopak from Crohn's Disease Donor

Cat. No.
XS-0426-XU235

Donor Age
Young Adult

Donor Health
Donors exhibit chronic transmural intestinal inflammation. The leukocyte profile is Th1/Th17 skewed, featuring expanded gut-tropic effector cells and markers of activated innate lymphoid cells.

Ethnicity
Diverse backgrounds available.

Anticoagulant
Acid Citrate Dextrose, designed to protect intestinal-homing T cells and stabilize the delicate balance of regulatory T cells.

Additional Donor Information
Each lot features a Leukopak from donors with histologically confirmed Crohn's Disease. Profiles include disease location, current CDAI scores, and history of biologic therapies to assist in investigating gut-homing lymphocyte subsets.

Clinical Profile
Disease location, surgical history related to disease, and history of biologic or immunosuppressive therapy.

Additional Information

Medication History
Available upon request. Includes history of aminosalicylates, corticosteroids, and significant exposure to biologics.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Crohn's Disease Donor, Leukopak, Crohn's Disease

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.