CellRapeutics™ Leukopak from Chronic Kidney Disease Donor (XS-0426-XU232)

Name: CellRapeutics™ Leukopak from Chronic Kidney Disease Donor
SKU: XS-0426-XU232
Rating: 5 (1 reviews)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Sourced from donors with varying stages of Chronic Kidney Disease, this Leukopak captures the cellular environment of uremic inflammation and immune senescence. The cell population typically exhibits a skewed monocyte distribution and altered T-cell proliferative capacities reflective of the systemic "inflammaging" characteristic of renal failure. This product is ideal for investigating the impact of metabolic toxins on leukocyte function and the immunological drivers of secondary cardiovascular complications in CKD patients.

Specific Inquiry

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Donor Information

Product Name
CellRapeutics™ Leukopak from Chronic Kidney Disease Donor

Cat. No.
XS-0426-XU232

Donor Age
Middle-Aged, Senior

Donor Health
Donors present with chronic renal dysfunction. The leukocyte profile is marked by signs of uremic toxin-induced immune dysfunction, featuring accelerated cellular senescence and altered innate immune reactivity.

Ethnicity
Diverse backgrounds available, predominantly African American and Hispanic cohorts.

Anticoagulant
Heparin, adjusted to accommodate potential donor uremic toxicity and preserve fragile leukocyte membranes.

Additional Donor Information
Each lot features a Leukopak from donors with clinically staged Chronic Kidney Disease. Profiles include eGFR levels, creatinine clearance data, and primary etiology, supporting research into systemic inflammation and myeloid dysfunction in renal failure.

Clinical Profile
Disease stage, primary etiology, and history of dialysis or renal replacement therapy.

Additional Information

Medication History
Available upon request. Documentation of antihypertensives, erythropoiesis-stimulating agents, phosphate binders, and history of dialysis if applicable.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Chronic Kidney Disease Donor, Leukopak, Chronic Kidney Disease

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.