CellRapeutics™ Leukopak from Cystic Fibrosis Donor (XS-0426-XU236)

Name: CellRapeutics™ Leukopak from Cystic Fibrosis Donor
SKU: XS-0426-XU236
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This Leukopak is harvested from donors diagnosed with Cystic Fibrosis, capturing the systemic immune consequences of CFTR dysfunction. The cells are conditioned by a lifetime of chronic pulmonary infections and contain neutrophils and macrophages with distinct functional phenotypes. This product is essential for research into the hyper-inflammatory innate responses and the impact of CFTR modulators on systemic leukocyte signaling.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Cystic Fibrosis Donor

Cat. No.
XS-0426-XU236

Donor Age
Young Adult

Donor Health
Leukocytes reflect systemic effects of CFTR dysfunction, characterized by chronic neutrophilic activation signatures and immune responses shaped by recurrent endobronchial infections.

Ethnicity
Predominantly Caucasian.

Anticoagulant
Heparin, selected to handle increased blood viscosity and preserve the functional viability of myeloid-derived suppressor cells.

Additional Donor Information
Each lot features a Leukopak from donors with genetically confirmed Cystic Fibrosis. Profiles include CFTR mutation types and history of chronic respiratory infections, supporting research into innate immune defects and neutrophil-driven inflammation.

Clinical Profile
Documented genetic mutations, respiratory function, and history of chronic pulmonary infections.

Additional Information

Medication History
Available upon request. Records of CFTR modulators, inhaled antibiotics, mucolytics, and pancreatic enzyme replacement therapy.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Cystic Fibrosis Donor, Leukopak, Cystic Fibrosis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.