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CellRapeutics™ Leukopak from Hypothyroidism Donor (XS-0426-XU247)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Derived from donors with primary Hypothyroidism, this Leukopak provides access to the peripheral immune environment conditioned by thyroid hormone deficiency. The specimens capture the systemic metabolic slowdown that influences leukocyte signaling and cytokine secretion patterns. It serves as a critical tool for researchers exploring the intersection of the endocrine and immune systems, specifically the impact of low thyroxine levels on the homeostatic maintenance of the lymphoid compartment.

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from Hypothyroidism Donor
  • Cat. No.
  • XS-0426-XU247
  • Donor Age
  • Middle-Aged, Senior
  • Donor Health
  • Donors exhibit a systemic hypometabolic state. The leukocyte profile may reflect altered cellular metabolic rates and subtle shifts in baseline immune signaling associated with thyroid hormone deficiency.
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • Acid Citrate Dextrose, focused on maintaining cellular mitochondrial membrane potential under altered metabolic conditions.
  • Additional Donor Information
  • Each lot features a Leukopak from donors with primary hypothyroidism. Profiles include TSH levels and hormone replacement dosages to support studies on the metabolic influence of thyroid hormones on immune cell function.
  • Clinical Profile
  • Etiology, duration of hormone replacement, and current TSH levels.

Additional Information

  • Medication History
  • Available upon request. Records of long-term Levothyroxine replacement and monitoring of TSH levels.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from Hypothyroidism Donor, Leukopak, Hypothyroidism

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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