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CellRapeutics™ Leukopak from Lupus Nephritis Donor (XS-0426-XU250)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Harvested from SLE donors with biopsy-confirmed renal involvement, this Leukopak captures the immune signatures specific to Lupus Nephritis. The cellular matrix is enriched with specific migratory subsets and inflammatory mediators that drive glomerular damage. This product is specifically curated for researchers focusing on the transition from systemic autoimmunity to target-organ injury and the identification of circulating biomarkers that correlate with renal histopathology and proteinuric flares.

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from Lupus Nephritis Donor
  • Cat. No.
  • XS-0426-XU250
  • Donor Age
  • Young Adult
  • Donor Health
  • Donors exhibit SLE with active renal involvement. The leukocyte profile reflects a severe autoimmune state with high titers of circulating immune complexes and expanded populations of renal-infiltrating precursors.
  • Ethnicity
  • Predominantly African American, Hispanic, and Asian cohorts.
  • Anticoagulant
  • Acid Citrate Dextrose or Heparin, optimized to stabilize the renal-homing lymphocyte population and maintain low activation backgrounds.
  • Additional Donor Information
  • Each lot features a Leukopak from SLE donors with biopsy-proven renal involvement. Profiles include proteinuria levels and histological class, specifically supporting research into the systemic drivers of autoimmune kidney damage.
  • Clinical Profile
  • Histological classification, renal function status, and history of intensive immunosuppression.

Additional Information

  • Medication History
  • Available upon request. Includes detailed history of intensive immunosuppressive induction and maintenance therapies.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from Lupus Nephritis Donor, Leukopak, Lupus Nephritis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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