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CellRapeutics™ Leukopak from Obesity Donor (XS-0426-XU285)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Derived from donors with a high Body Mass Index, this Leukopak reflects the chronic "metainflammation" characteristic of adipose tissue expansion. The cellular matrix is enriched with proinflammatory M1-polarized monocyte precursors and Th17-skewed T-cell subsets. It serves as a primary substrate for investigating the link between metabolic syndrome and the systemic dysregulation of innate and adaptive immune responses.

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from Obesity Donor
  • Cat. No.
  • XS-0426-XU285
  • Donor Age
  • Young Adult, Middle-Aged
  • Donor Health
  • Donors classified as obese. Leukocytes reflect "metainflammation," showing a chronic pro-inflammatory bias in monocytes and a metabolic-driven shift in T-cell subset distribution.
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • Heparin, optimized to prevent interference from high plasma lipid content and preserve monocyte/macrophage polarization.
  • Additional Donor Information
  • Each lot features a Leukopak from donors with a BMI ≥ 30 kg/m². Profiles include metabolic markers to facilitate research into the impact of adipose tissue inflammation on peripheral leukocyte function.
  • Clinical Profile
  • Body Mass Index category, waist circumference, history of related metabolic syndromes, and documentation of lifestyle or surgical interventions.

Additional Information

  • Medication History
  • Available upon request. Includes history of anti-obesity medications, and medications for associated metabolic syndromes like dyslipidemia or insulin resistance.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from Obesity Donor, Leukopak, Obesity

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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