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CellRapeutics™ Leukopak from Osteoarthritis Donor (XS-0426-XU256)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Procured from donors with clinical and radiographic evidence of Osteoarthritis, this Leukopak reflects the low-grade systemic inflammatory component of degenerative joint disease. The cell population is characterized by distinct monocyte activation patterns and alterations in the innate immune compartment linked to cartilage catabolism. This product supports research into the "inflammaging" aspect of OA and the systemic drivers of joint-related chronic pain and disability.

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from Osteoarthritis Donor
  • Cat. No.
  • XS-0426-XU256
  • Donor Age
  • Senior
  • Donor Health
  • Clinically diagnosed with degenerative Osteoarthritis. The leukocyte population exhibits a low-grade systemic inflammatory profile, specifically showing alterations in monocyte-derived macrophage polarization related to cartilage metabolic turnover.
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • Acid Citrate Dextrose, standard high-viability formulation to preserve innate immune cell subsets and senescent cell markers.
  • Additional Donor Information
  • Each lot features a Leukopak from donors with radiographically confirmed OA. Profiles include joint involvement sites and pain severity, supporting research into the role of low-grade systemic inflammation in degenerative joint disease.
  • Clinical Profile
  • Affected joints, Kellgren-Lawrence radiographic grading, pain/functionality scores, and history of intra-articular injections or orthopedic interventions.

Additional Information

  • Medication History
  • Available upon request. Documentation of chronic NSAID use, analgesics, and history of intra-articular corticosteroid or hyaluronic acid injections.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from Osteoarthritis Donor, Leukopak, Osteoarthritis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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