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CellRapeutics™ Leukopak from Relapsing-Remitting Multiple Sclerosis Donor (XS-0426-XU291)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This Leukopak provides a comprehensive leucocyte profile harvested from donors clinically diagnosed with Relapsing-Remitting Multiple Sclerosis. The cellular composition captures the dynamic fluctuations of the systemic immune system characteristic of this disease, featuring an enriched repertoire of autoreactive T-cell subsets and memory B cells primed for neuro-antigen recognition. It serves as a high-yield source for investigating the mechanisms of episodic blood-brain barrier penetration and the efficacy of disease-modifying therapies on peripheral immune cell activation.

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from Relapsing-Remitting Multiple Sclerosis Donor
  • Cat. No.
  • XS-0426-XU291
  • Donor Age
  • Young Adult
  • Donor Health
  • Clinically diagnosed with RRMS. The leukocyte population is characterized by a phasic neuro-inflammatory profile, showing episodic expansion of Th1/Th17 effector subsets and a high frequency of immune cells with enhanced blood-brain barrier migratory potential.
  • Ethnicity
  • Diverse backgrounds available, predominantly Caucasian.
  • Anticoagulant
  • Acid Citrate Dextrose, prioritized to capture the dynamic shift in T cell subsets while maintaining their quiescent or activated states.
  • Additional Donor Information
  • Each lot features a Leukopak from donors with RRMS. Profiles include relapse frequency and history of disease-modifying therapies, ideal for studying the episodic nature of autoimmune neuro-inflammation.
  • Clinical Profile
  • Confirmed RRMS diagnosis, time since last relapse, EDSS score, and detailed history of disease-modifying therapies.

Additional Information

  • Medication History
  • Available upon request. Comprehensive records of Disease-Modifying Therapies including injectables, orals, or high-efficacy infusion therapies.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from Relapsing-Remitting Multiple Sclerosis Donor, Leukopak, Relapsing-Remitting Multiple Sclerosis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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