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CellRapeutics™ Serum from AChR+ Myasthenia Gravis Donor (XS-0426-XU12)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This serum contains high titers of autoantibodies against the nicotinic Acetylcholine Receptor. It is an indispensable tool for researchers studying the neuromuscular junction's pathophysiology, complement-mediated membrane damage, and for developing diagnostic assays or therapeutic interventions targeting antibody-mediated muscle weakness.

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Donor Information

  • Product Name
  • CellRapeutics™ Serum from AChR+ Myasthenia Gravis Donor
  • Cat. No.
  • XS-0426-XU12
  • Donor Age
  • Young Adult, Senior
  • Donor Health
  • Diagnosed with Myasthenia Gravis with confirmed positive Acetylcholine Receptor antibodies. The serum contains disease-specific pathogenic autoantibodies and related complement-activating factors.
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • None (separated via centrifugation following natural coagulation).
  • Additional Donor Information
  • Each lot features serum from donors with clinically confirmed AChR-antibody positive Myasthenia Gravis. Profiles include AChR-Ab titers, MGFA clinical classification, and history of thymectomy or acetylcholinesterase inhibitor therapy.
  • Clinical Profile
  • Documented anti-acetylcholine receptor antibody titers, disease severity, and current immunosuppressive therapy.

Additional Information

  • Medication History
  • Available upon request. Includes records of Acetylcholinesterase inhibitors, immunosuppressants, and recent history of intravenous immunoglobulin or plasmapheresis.
  • Formulation
  • Frozen
  • Cell Viability
  • Cell-free (no residual erythrocytes or leukocytes).
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each serum batch undergoes rigorous IRB-compliant screening, ensuring pathogen-free safety, consistent physicochemical properties, and standardized clinical characterization of disease-specific biomarkers to provide a reliable, high-purity biological matrix.
  • Storage
  • Store at -80°C or below for long-term stability, or at -20°C for up to 6 months, avoid repeated freeze-thaw cycles to preserve product quality.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Thaw slowly on ice or at 4°C and centrifuge to remove cryoprecipitates, immediate aliquoting upon first thaw is recommended to maintain autoantibody functional integrity.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • 1ML
  • Keywords
  • CellRapeutics™ Serum from AChR+ Myasthenia Gravis Donor, Serum, AChR+ Myasthenia Gravis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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