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CellRapeutics™ Serum from Limited Cutaneous Systemic Sclerosis Donor (XS-0426-XU119)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product features serum from donors with lcSSc. It is characterized by the presence of anti-centromere antibodies (ACA) and a distinctive cytokine profile associated with localized skin involvement and digital vasculopathy. It is a critical reagent for researchers focusing on the vascular and fibrotic mediators that distinguish limited from diffuse systemic sclerosis.

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Donor Information

  • Product Name
  • CellRapeutics™ Serum from Limited Cutaneous Systemic Sclerosis Donor
  • Cat. No.
  • XS-0426-XU119
  • Donor Age
  • Middle-Aged
  • Donor Health
  • Diagnosed with Limited Scleroderma. Serum is distinguished by high titers of anti-centromere antibodies and markers reflecting localized skin thickening and vascular involvement.
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • None (separated via centrifugation following natural coagulation).
  • Additional Donor Information
  • Each lot features serum from donors with lcSSc. Profiles include anti-centromere antibody status, documentation of Raynaud's phenomenon, and skin involvement scoring.
  • Clinical Profile
  • Presence of CREST syndrome features, anti-centromere antibody status, and modified Rodnan Skin Score.

Additional Information

  • Medication History
  • Available upon request. Documentation of treatments for Raynaud's phenomenon, vasodilators, and mild immunomodulatory interventions.
  • Formulation
  • Frozen
  • Cell Viability
  • Cell-free (no residual erythrocytes or leukocytes).
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each serum batch undergoes rigorous IRB-compliant screening, ensuring pathogen-free safety, consistent physicochemical properties, and standardized clinical characterization of disease-specific biomarkers to provide a reliable, high-purity biological matrix.
  • Storage
  • Store at -80°C or below for long-term stability, or at -20°C for up to 6 months, avoid repeated freeze-thaw cycles to preserve product quality.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Thaw slowly on ice or at 4°C and centrifuge to remove cryoprecipitates, immediate aliquoting upon first thaw is recommended to maintain autoantibody functional integrity.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • 1ML
  • Keywords
  • CellRapeutics™ Serum from Limited Cutaneous Systemic Sclerosis Donor, Serum, Limited Cutaneous Systemic Sclerosis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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