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Expanded TIL Functional Testing Services

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Tumor-infiltrating lymphocyte (TIL) therapy has emerged as a promising immunotherapy approach, specifically for melanoma and other cancers. The process begins with isolating lymphocytes from the patient's tumor, followed by their expansion in vitro. These expanded TILs are then reintroduced into the patient, aiming to target and eliminate cancer cells. Functional assays play an important role in the development and optimization of TIL therapeutics. At Creative Biolabs, we offer comprehensive services designed to maximize the therapeutic potential of TILs through precise expansion and functional testing. Our functional assay services include a variety of assays designed to evaluate the cytotoxicity and cytokine release capabilities of expanded TILs, ensuring their therapeutic potential.

Functional Assay Service Options

Fig.1 Expanded TIL cytotoxicity assay. (Creative Biolabs original)

Expanded TIL Cytotoxicity Assay

Our cytotoxicity assays are designed to measure the ability of expanded TILs to effectively kill cancer cells. This assay provides direct evidence of the cytotoxic potential of TILs, ensuring they retain their anti-tumor activity post-expansion.

Learn More about Our Cytotoxicity Assay→

Fig.2 Expanded TIL cytokine release assay. (Creative Biolabs original)

Expanded TIL Cytokine Release Assay

Our cytokine release assays are meticulously designed to quantify the release of key cytokines, such as IFN-gamma, TNF-alpha, and IL-2, which are indicative of TIL activation and functionality.

Learn More about Our Cytokine Release Assay→

The Promise of Expanded TIL Functional Testing Service

By leveraging cutting-edge technologies and methodologies, Creative Biolabs is committed to enhancing the therapeutic potential of TIL therapy. Our functional assays help determine the ability of TILs to recognize and destroy cancer cells, and their capacity to produce critical cytokines — factors that are vital for anti-tumor responses. We have a team of experienced scientists to deliver precise, reliable, and reproducible results. We partner with our clients, offering tailored solutions and expert guidance throughout the testing process, ensuring that each therapeutic development journey is supported by the highest standards of scientific rigor. We promise precision, reliability, and a commitment to helping our partners achieve groundbreaking advances in cancer immunotherapy.

One-stop TIL Development Platform

At Creative Biolabs, we are dedicated to supporting every stage of the TIL development process. From the initial isolation of TILs to their expansion and functional testing, our integrated services are designed to meet the diverse needs of global clients. By integrating each stage of TIL development under one platform, we ensure continuity, consistency, and quality that expedite the journey from research to therapy.

Contact us today to explore how our experts support your journey in developing TIL therapies.

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