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HighTransm™ Anti-Human AXL h(41BB-CD3ζ) CAR Lentivirus Kit (XS-0326-XL40)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This system streamlines the generation of AXL-specific CAR-T cells, targeting tyrosine kinase signaling in aggressive, drug-resistant solid tumor models.

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Description

  • Target
  • AXL
  • Components
  • This kit contains a AXL CAR lentiviral vector, a lentiviral packaging plasmid mix, and an LV high transfection reagent.
  • Size
  • for 10 cm dish packaging; for 15 cm dish packaging
  • Storage Conditions
  • For details of the storage requirements, please see the User Manual for instructions.
  • Applications
  • CAR lentivirus packaging

CAR Vector

  • CAR Generation
  • 2nd-generation CAR
  • Vector Name
  • pCDCAR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral vector
  • Receptor Construction
  • scFv-41BB-CD3ζ

Target

  • Gene Name
  • UFO
  • Full Name
  • AXL receptor tyrosine kinase
  • Target Species
  • Human
  • Gene ID
  • 558
  • Uniprot ID
  • P30530
  • Target Background
  • This TAM family kinase governs epithelial-to-mesenchymal transition and promotes therapeutic resistance in diverse solid tumors.
  • Related Disease
  • NSCLC; Pancreatic Cancer; AML

Case Studies

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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