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HighTransm™ Anti-Human EPCAM h(41BB-CD3ζ) CAR Lentivirus Kit (XS-0326-XL12)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Drive your EpCAM-directed therapy projects forward with our specialized kit, engineered for consistent production of high-titer, therapeutic-grade CAR lentiviral vectors.

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Description

  • Target
  • EPCAM
  • Components
  • This kit contains an EPCAM CAR lentiviral vector, a lentiviral packaging plasmid mix, an LV high transfection reagent.
  • Size
  • for 10 cm dish packaging; for 15 cm dish packaging
  • Storage Conditions
  • For details of the storage requirements, please see the User Manual for instructions.
  • Applications
  • CAR lentivirus packaging

CAR Vector

  • CAR Generation
  • 2nd-generation CAR
  • Vector Name
  • pCDCAR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral vector
  • Receptor Construction
  • scFv-41BB-CD3ζ

Target

  • Gene Name
  • CD326
  • Full Name
  • Epithelial cell adhesion molecule
  • Target Species
  • Human
  • Gene ID
  • 4072
  • Uniprot ID
  • P16422
  • Target Background
  • A pan-epithelial adhesion molecule overexpressed in carcinomas, involved in cell signaling, migration, and serving as a target for immunotherapy.
  • Related Disease
  • Epithelial carcinomas; Lynch syndrome; Congenital tufting enteropathy; Ovarian cancer

Case Studies

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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