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Anti-CTP synthase T cell receptor (JL12), pCDTCR1 (TCR-C036Z)

The vector of anti-CTP synthase T cell receptor (TCR) is constructed for the engineering of T cell to target Human CTP synthase. The T cells are genetically modified through transduction with a lentiviral vector expressing CTP synthase-specific T cell receptor.

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Details

  • Target
  • CTP synthase
  • Target Species
  • Human
  • Epitope
  • KPSPPYFGL
  • Format
  • Non-modified
  • HLA
  • HLA-B35
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Antibody Clone
  • JL12
  • Antibody Host
  • Human

Target

  • Official Symbol
  • CTPS1
  • Introduction
  • This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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