Anti-DLBCL T cell receptor (alpha6 beta13), pCDTCR1(TCR-C039Z)

The vector of anti-DLBCL T cell receptor (TCR) is constructed for the engineering of T cell to target Human DLBCL. The T cells are genetically modified through transduction with a lentiviral vector expressing DLBCL-specific T cell receptor. And the vector product was designed for the treatment of Lymphoma.


Details


Target
DLBCL
Target Species
Human
Format
Non-modified
HLA
HLA-A2
Targeting Diseases
Lymphoma
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
alpha6 beta13
Antibody Host
Human

Target


Gene Name
Diffuse large B-cell lymphoma
Official Symbol
DLBCL
Synonyms
DLBCL; Diffuse large B-cell lymphoma
Introduction
Diffuse large B-cell lymphoma (DLBCL or DLBL) is a cancer of B cells, a type of white blood cell responsible for producing antibodies. It is the most common type of non-Hodgkin lymphoma among adults, with an annual incidence of 7–8 cases per 100,000 people per year. This cancer occurs primarily in older individuals, with a median age of diagnosis at approximately 70 years of age, though it can also occur in children and young adults in rare cases. DLBCL is an aggressive tumor which can arise in virtually any part of the body, and the first sign of this illness is typically the observation of a rapidly growing mass, sometimes associated with B symptoms—fever, weight loss, and night sweats.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products


Lymphoma

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Fax: 1-631-207-8356
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