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IHC-based Expanded TIL Phenotypic Profiling Service

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Tumor-infiltrating lymphocytes (TILs) play a pivotal role in the immune response against cancer. These lymphocytes infiltrate tumor tissues and are often associated with improved patient prognoses in various cancers. At Creative Biolabs, our advanced IHC-based service provides comprehensive profiling of TIL phenotypes, employing state-of-the-art instrumentation and expertly designed multiparametric panels.

IHC Based-TIL Phenotypic Profiling Services

At Creative Biolabs, we are committed to providing cutting-edge TIL phenotypic profiling services that leverage our expertise in IHC. Our IHC services utilize state-of-the-art techniques to visualize and characterize immune cell populations directly within tissue samples, allowing for precise assessment of their distribution, activation status, and interactions with tumor cells. With our expert guidance and high-quality staining protocols, researchers can uncover critical information about immune responses in various cancers, paving the way for innovative therapeutic approaches and personalized medicine.

Our IHC Capabilities

  • Various TIL Markers Staining

We employ state-of-the-art IHC techniques to stain tissue samples for various TIL markers, including CD8, CD4, FoxP3, and PD-1. This allows for the precise identification and localization of different TIL populations within the tumor microenvironment.

  • Comprehensive TIL Subset Characterization

Our service provides an extensive analysis of TIL phenotypes, covering a wide array of subsets such as CD8+, CD4+, and Tregs. This comprehensive profiling helps in understanding the TIL heterogeneity and predicting responses to immunotherapies.

  • Customized IHC Panels

Recognizing that each research project is unique, we offer customized IHC panels tailored to specific research needs. Whether you require a focus on specific TIL populations or additional markers to assess tumor characteristics, our team will work closely with you to develop the ideal panel.

  • Multiplexing Capability

Our service incorporates multiplex IHC, allowing the simultaneous detection of multiple biomarkers. This capability provides a more detailed picture of TIL interactions and their functional status in situ, which is invaluable for comprehensive immune profiling.

  • Professional Team

Our team of experienced pathologists and immunologists provides comprehensive consultation services. We ensure that you understand the implications of the data, offering detailed reports that contextualize the findings within your research framework.

How We Support TIL Therapy Programs

At Creative Biolabs, our comprehensive service provides end-to-end support for the development of TIL-based immunotherapies, including TIL isolation, robust expansion protocols, and thorough phenotypic profiling through IHC. We are committed to offering clients a detailed look into the makeup of expanded TILs. Through IHC, we assess the expression of activation markers, exhaustion markers, and subsets like CD8+ T cells, which are crucial for ensuring the TILs remain potent and functionally capable.

If you're seeking a reliable partner to support your TIL therapy program with phenotypic profiling services for expanded TILs, we're here to help. Contact us to discuss how our IHC services support your TIL therapy project.

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