Lenti-CD20 CAR (scFv-ζ, Ofatumumab)-VP(VP-CAR-LC770)

The ready-to-use lentiviral particles of Lenti-CD20 CAR (scFv-ζ, Ofatumumab)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (Ofatumumab)-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.


Specifications


Type of Therapeutics
Chimeric Antigen Receptor
Target
CD20
Expression Cassette
scFv (Ofatumumab)-CD3ζ
Clone
Ofatumumab
Promotor
EF1a
Packaging System
Lentivirus
Packaging Cell
293T
Targeting Diseases
Chronic lymphocytic leukemia (CLL)

Target


Introduction
This gene encodes a member of the membrane-spanning 9A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic
Alternative Names
Membrane Spanning 4-Domains A1; Membrane-Spanning 4-Domains, Subfamily A, Member 1; Leukocyte Surface Antigen Leu-16; CD20 Antigen; CD20; Bp35; Membrane-Spanning 4-Domains Subfamily A Member 1; B-Lymphocyte Cell-Surface Antigen B1; B-Lymphocyte Surface Antigen B1;
Gene ID

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Tel: 44-207-097-1828

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