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Lenti-CD20 CAR (scFv-ζ, Leu-16)-VP (VP-CAR-LC746)

The ready-to-use lentiviral particles of Lenti-CD20 CAR (scFv-ζ, Leu-16)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (Leu-16)-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.

Specifications

  • Type of Therapeutics
  • Chimeric Antigen Receptor
  • Target
  • CD20
  • Expression Cassette
  • scFv (Leu-16)-CD3ζ
  • Clone
  • Leu-16
  • Promotor
  • EF1a
  • Packaging System
  • Lentivirus
  • Packaging Cell
  • 293T
  • Targeting Diseases
  • Recurrent/refractory CD20+ lymphoma

Target

  • Introduction
  • This gene encodes a member of the membrane-spanning 9A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic
  • Alternative Names
  • Membrane Spanning 4-Domains A1; Membrane-Spanning 4-Domains, Subfamily A, Member 1; Leukocyte Surface Antigen Leu-16; CD20 Antigen; CD20; Bp35; Membrane-Spanning 4-Domains Subfamily A Member 1; B-Lymphocyte Cell-Surface Antigen B1; B-Lymphocyte Surface Antigen B1;

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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