Lenti-CD5 CAR (scFv-28ζ, H65)-VP(VP-CAR-LC656)

The ready-to-use lentiviral particles of Lenti-CD5 CAR (scFv-28ζ, H65)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (H65)-CD28-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.


Specifications


Type of Therapeutics
Chimeric Antigen Receptor
Target
CD5
Expression Cassette
scFv (H65)-CD28-CD3ζ
Clone
H65
Promotor
CMV
Packaging System
Lentivirus
Packaging Cell
293T
Targeting Diseases
Acute Lymphoblastic Leukemia

Target


Introduction
This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Names
CD5; CD5 molecule; T1; LEU1
Gene ID

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Leukemia

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
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Tel: 44-207-097-1828

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