Lenti-p53 TCR (Cysteine-modified)-VP (VP-TCR-C532)

The ready-to-use lentiviral particles of Lenti-p53 TCR (Cysteine-modified)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of Murinized (from Human) TCR will be driven by a CMV promotor. The target gene of TCR packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.

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  • Type of Therapeutics
  • T cell receptor
  • Target
  • p53
  • Promotor
  • CMV
  • Packaging System
  • Lentivirus
  • Packaging Cell
  • 293T
  • Targeting Diseases
  • Cancer, allergies, viral infections and autoimmune disorders.


  • Introduction
  • TP53 is a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. TP53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome.
  • Alternative Names
  • TP53; Tumor Protein P53; Phosphoprotein P53; Antigen NY-CO-13; P53; Transformation-Related Protein 53; Cellular Tumor Antigen P53; Mutant Tumor Protein 53; Li-Fraumeni Syndrome

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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