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Lenti-Tyrosinase TCR (Codon optimized)-VP (VP-TCR-C574)

The ready-to-use lentiviral particles of Lenti-Tyrosinase TCR (Codon optimized)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of Human TCR will be driven by a CMV promotor. The target gene of TCR packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.

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Specifications

  • Type of Therapeutics
  • T cell receptor
  • Target
  • Tyrosinase
  • Promotor
  • CMV
  • Packaging System
  • Lentivirus
  • Packaging Cell
  • 293T
  • Targeting Diseases
  • Melanoma

Target

  • Introduction
  • TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. TYR has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in TYR result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of TYR.
  • Alternative Names
  • TYR; Tyrosinase; Oculocutaneous Albinism IA; Tumor Rejection Antigen AB; Monophenol Monooxygenase; EC 1.14.18.1; LB24-AB; SK29-AB

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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