Tyrosinase

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

Associated Disease

TCR Vector Products Product list:

Catalog Target Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Vector
Type
Epitope Format HLA Data
sheet
Price
TCR-L116Z tyrosinase Human Human 8kb Lentiviral YMNGTMSQV Non-modified HLA-A*0201 Inquiry
TCR-L117 tyrosinase Human Human 6714-6688bp retroviral vector YMDGTMSQV Non-modified TCR HLA-A*0201 Inquiry
TCR-L117Z tyrosinase Human Murinized (from Human) 8kb Lentiviral YMNGTMSQV Murinized HLA-A2 Inquiry
TCR-L118 tyrosinase Human Murinized (from Human) 6700-8070bp retroviral vector YMDGTMSQV Murinized TCR HLA-A2 Inquiry
TCR-L118Z tyrosinase Human Murinized (from Human) 8kb Lentiviral YMNGTMSQV Murinized and Cysteine-modified HLA-A2 Inquiry
TCR-L119 tyrosinase Human Murinized (from Human) 6700-8070bp retroviral vector YMDGTMSQV Murinized and cysteine-modified TCR HLA-A2 Inquiry
TCR-L119Z tyrosinase Human Human 8kb Lentiviral YMNGTMSQV Codon optimized HLA-A2 Inquiry
TCR-L120 tyrosinase Human Human 3817bp retroviral vector YMDGTMSQV Codon optimized TCR HLA-A2 Inquiry
TCR-L213 Tyrosinase Human T58 Human ~8kb Lentiviral YMDGTMSQV Non-modified HLA-A*0201 Inquiry
TCR-L256 Tyrosinase Human T43 Human ~8kb Lentiviral YMDGTMSQV Non-modified HLA-A*0201 Inquiry
TCR-L257 Tyrosinase Human di111 Human ~8kb Lentiviral YMDGTMSQV Non-modified HLA-A*0201 Inquiry
TCR-L258 Tyrosinase Human B12 Human ~8kb Lentiviral YMDGTMSQV Non-modified HLA-A*0201 Inquiry

TCR Viral Particles Product list:

Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Packaging
System
Epitope Format Titer Data
sheet
Price
VP-TCR-C568 Human T58 Human Lentivirus YMDGTMSQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C569 Human T43 Human Lentivirus YMDGTMSQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C570 Human di111 Human Lentivirus YMDGTMSQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C571 Human B12 Human Lentivirus YMDGTMSQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C572 Human Murinized (from Human) Lentivirus YMDGTMSQV Murinized TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C573 Human Murinized (from Human) Lentivirus YMDGTMSQV Murinized and Cysteine-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C574 Human Human Lentivirus YMDGTMSQV Codon optimized TCR > 10⁷ IFU/ml Inquiry
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