The vector of anti-CAIX chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CAIX. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CAIX antibody linked to CD3-zeta signaling domains. And the vector product was designed for the treatment of renal cell carcinoma (RCC).
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC51||Lenti-CAIX CAR (scFv-CD3ζ, G250) Viral Particle|
|CAR-T-1-M305-G||Anti-CAIX scFv h(FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC58||Lenti-CAIX CAR (scFv-b2c-CD3ζ, G250) Viral Particle|
|VP-CAR-LC891||Lenti-Carbonic anhydrase IX (CA9) CAR (scFv-CD28-CD3ζ, G36) Viral Particle|
|CAR-MZ205||Anti-CAIX (G36) h(CD28-OX40-CD3ζ) CAR, pCDCAR1|
|CAR-T-1-L404-G||G250 h(FcεRIγ) CAR, [T]|
|CAR-T-2-M305-4G||Anti-CAIX scFv h(CD4-FcεRIγ) CART, pCDCAR1|
|CAR-T-2-L404-2Z||G250 h(CD28-CD3ζ) CAR, [T]|
|CAR-T-3-L404-2BZ||G250 h(CD28-41BB-CD3ζ) CAR, [T]|
|CAR-MZ203||Anti-CAIX (G36) h(41BB-CD3ζ) CAR, pCDCAR1|
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