The vector of anti-ErbB2 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human ErbB2. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-ErbB2 antibody linked to a CD28 transmembrane domain/ endodomain and FcεRIγ signaling domains. And the vector product was designed as a medicament, in particular in the treatment of cancer and in adoptive, target-cell specific immunotherapy.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-TCR-C128||Lenti-HER2 (TYLPTNASL) T cell receptor Viral Particle|
|CAR-MZ136||Anti-ErbB2 (N29) h(CD28-FcγR) CAR, pCDCAR1|
|TCR-C098Z||Murinized anti-HER2 T cell receptor (HER2-2), pCDTCR1|
|CAR-T-3-M550-2BZ||Anti-HER2 VHH h(CD28-41BB-CD3ζ) CAR, [T]|
|CAR-T-3-L337-2XZ||Anti-ErbB2 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1|
|CAR-T-2-M550-BZ||Anti-HER2 VHH h(41BB-CD3ζ) CAR, [T]|
|VP-CAR-LC231||Lenti-ErbB2 CAR (scFv-CD28-41BB-CD3ζ, OTI5C4) Viral Particle|
|VP-CAR-LC230||Lenti-ErbB2 CAR (scFv-b2c-CD3ζ, OTI5C4) Viral Particle|
|CAR-NK-2-M331-4Z||Anti-ErbB2 scFv h(CD4-CD3ζ) CARNK, pCDCAR1|
|TCR-L049Z||Human anti-HER2 T cell receptor, pCDTCR1|
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