The vector of anti-PD-1 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human PD-1. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-PD-1 antibody linked to CD3-zeta signaling domains. And the vector product was designed for the treatment of B-cell malignancies.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC405||Lenti-PD-1 CAR (scFv-CD28-CD3ζ, J43) Viral Particle|
|VP-CAR-LC412||Lenti-PD-1 CAR (scFv-CD28-OX40-CD3ζ, J43) Viral Particle|
|CAR-T-2-L345-2G||Anti-PD-1 scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|CAR-T-2-L345-4Z||Anti-PD-1 scFv h(CD4-CD3ζ) CART, pCDCAR1|
|CAR-T-2-L345-CZ||Anti-PD-1 scFv h(b2c-CD3ζ) CART, pCDCAR1|
|CAR-T-2-L345-2Z||Anti-PD-1 scFv h(CD28-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC401||Lenti-PD-1 CAR (scFv-CD28, J43) Viral Particle|
|CAR-T-1-L345-G||Anti-PD-1 scFv h(FcεRIγ) CART, pCDCAR1|
|CAR-T-2-L345-BZ||Anti-PD-1 scFv h(41BB-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC409||Lenti-PD-1 CAR (scFv-41BB-CD3ζ, J43) Viral Particle|
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