The vector of anti-ROR1 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human ROR1. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-ROR1 antibody linked to CD3-zeta signaling domains. And the vector product was designed for the treatment of B cell-chronic lymphocytic leukemia (B-CLL) and MCL tumor.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-T-2-M324-8Z||Anti-ROR1 scFv h(CD8-CD3ζ) CART, pCDCAR1|
|CAR-MZ178||Anti-ROR1 (4A5) h(CD28-OX40-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC425||Lenti-ROR1 CAR (scFv-CD28, 2A2) Viral Particle|
|CAR-T-2-M324-CZ||Anti-ROR1 scFv h(b2c-CD3ζ) CART, pCDCAR1|
|CAR-LC344||Anti-ROR1 (2A4) h(41BB/CD3ζ) Multi-chain CAR, pCDCAR1|
|CAR-LC341||Anti-ROR1 (G6) h(41BB/CD3ζ) Multi-chain CAR, pCDCAR1|
|CAR-LC345||Anti-ROR1 (1C11) h(41BB/CD3ζ) Multi-chain CAR, pCDCAR1|
|VP-CAR-LC427||Lenti-ROR1 CAR (scFv-CD3ζ, 2A2) Viral Particle|
|VP-CAR-LC870||Lenti-ROR1 CAR (scFv-CD3ζ, 4A5) Viral Particle|
|VP-CAR-LC426||Lenti-ROR1 CAR (scFv-FcεRIγ, 2A2) Viral Particle|
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