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HIV-1 gp120

Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. GP120 is essential for virus entry into cells as it plays a vital role in attachment to specific cell surface receptors. This molecule has specific interaction with the CD4 receptor of helper T cells. Binding to CD4 induces the start of a cascade of conformational changes in gp120 and gp41 that lead to the fusion of the viral with the host cell membrane. Since CD4 receptor binding is the most obvious step in HIV infection, gp120 was among the first targets of HIV vaccine research.

Associated Disease
  • CAR Vector Products
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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-LC026 Anti-HIV-1 gp120 (PGT145) h(41BB-CD3ζ) CAR, pCDCAR1 HIV PGT145 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC289 Anti-HIV-1 gp120 CD4-h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human Human CD4-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC290 Anti-HIV-1 gp120 CD4-scFv-17b-h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human 17b Human CD4-35-scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC291 Anti-HIV-1 gp120 h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human 17b Human CD4-10-scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC292 Anti-HIV-1 gp120 CD4-scFv-DDY3-h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human DDY3 Human CD4-35-scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-ZP1850 Anti-HIV-1 gp120 (GP44) h(CD28-CD3ζ) CAR, pCDCAR1 Human GP44 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1851 Anti-HIV-1 gp120 (GP44) h(41BB-CD3ζ) CAR, pCDCAR1 Human GP44 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1852 Anti-HIV-1 gp120 (PGT145) h(CD28-CD3ζ) CAR, pCDCAR1 Human PGT145 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1853 Anti-HIV-1 gp120 (PGT145) h(41BB-CD3ζ) CAR, pCDCAR1 Human PGT145 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1854 Anti-HIV-1 gp120 (F56/P6G4) h(CD28-CD3ζ) CAR, pCDCAR1 Human F56/P6G4 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1855 Anti-HIV-1 gp120 (F56/P6G4) h(41BB-CD3ζ) CAR, pCDCAR1 Human F56/P6G4 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1856 Anti-HIV-1 gp120 (25C2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 25C2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1857 Anti-HIV-1 gp120 (25C2) h(41BB-CD3ζ) CAR, pCDCAR1 Human 25C2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1858 Anti-HIV-1 gp120 (8ANC195) h(CD28-CD3ζ) CAR, pCDCAR1 Human 8ANC195 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1859 Anti-HIV-1 gp120 (8ANC195) h(41BB-CD3ζ) CAR, pCDCAR1 Human 8ANC195 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1860 Anti-HIV-1 gp120 (PGT-130) h(CD28-CD3ζ) CAR, pCDCAR1 Human PGT-130 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1861 Anti-HIV-1 gp120 (PGT-130) h(41BB-CD3ζ) CAR, pCDCAR1 Human PGT-130 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1862 Anti-HIV-1 gp120 (830A) h(CD28-CD3ζ) CAR, pCDCAR1 Human 830A Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1863 Anti-HIV-1 gp120 (830A) h(41BB-CD3ζ) CAR, pCDCAR1 Human 830A Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1864 Anti-HIV-1 gp120 (A12) h(CD28-CD3ζ) CAR, pCDCAR1 Human A12 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1865 Anti-HIV-1 gp120 (A12) h(41BB-CD3ζ) CAR, pCDCAR1 Human A12 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1866 Anti-HIV-1 gp120 (BAT123) h(CD28-CD3ζ) CAR, pCDCAR1 Human BAT123 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1867 Anti-HIV-1 gp120 (BAT123) h(41BB-CD3ζ) CAR, pCDCAR1 Human BAT123 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1868 Anti-HIV-1 gp120 (VRC01) h(CD28-CD3ζ) CAR, pCDCAR1 Human VRC01 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1869 Anti-HIV-1 gp120 (VRC01) h(41BB-CD3ζ) CAR, pCDCAR1 Human VRC01 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1870 Anti-HIV-1 gp120 (L91E1) h(CD28-CD3ζ) CAR, pCDCAR1 Human L91E1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1871 Anti-HIV-1 gp120 (L91E1) h(41BB-CD3ζ) CAR, pCDCAR1 Human L91E1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1872 Anti-HIV-1 gp120 (49B11/A1) h(CD28-CD3ζ) CAR, pCDCAR1 Human 49B11/A1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1873 Anti-HIV-1 gp120 (49B11/A1) h(41BB-CD3ζ) CAR, pCDCAR1 Human 49B11/A1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1874 Anti-HIV-1 gp120 (DH285) h(CD28-CD3ζ) CAR, pCDCAR1 DH285 Mouse scFv-CD28-CD3ζ   Add to Cart   Datasheet
CAR-ZP1875 Anti-HIV-1 gp120 (DH285) h(41BB-CD3ζ) CAR, pCDCAR1 Human DH285 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1876 Anti-HIV-1 gp120 (PGT135) h(CD28-CD3ζ) CAR, pCDCAR1 Human PGT135 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1877 Anti-HIV-1 gp120 (PGT135) h(41BB-CD3ζ) CAR, pCDCAR1 Human PGT135 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1878 Anti-HIV-1 gp120 (R56) h(CD28-CD3ζ) CAR, pCDCAR1 Human R56 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1879 Anti-HIV-1 gp120 (R56) h(41BB-CD3ζ) CAR, pCDCAR1 Human R56 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1880 Anti-HIV-1 gp120 (1.4E) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1.4E Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1881 Anti-HIV-1 gp120 (1.4E) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1.4E Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1882 Anti-HIV-1 gp120 (CAP257-RH1) h(CD28-CD3ζ) CAR, pCDCAR1 Human CAP257-RH1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1883 Anti-HIV-1 gp120 (CAP257-RH1) h(41BB-CD3ζ) CAR, pCDCAR1 Human CAP257-RH1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP1884 Anti-HIV-1 gp120 (PGT121) h(CD28-CD3ζ) CAR, pCDCAR1 Human PGT121 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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