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HLA-DQB1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WFY0682 Anti-HLA-DQB1 (SK10) h(41BB-CD3ζ) CAR, pCDCAR1 Human SK10 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1147 Anti-HLA-DQB1 (B-K27) h(41BB-CD3ζ) CAR, pCDCAR1 Human B-K27 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1148 Anti-HLA-DQB1 (BL-A/G3) h(41BB-CD3ζ) CAR, pCDCAR1 Human BL-A/G3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1149 Anti-HLA-DQB1 (ICO-1) h(41BB-CD3ζ) CAR, pCDCAR1 Human ICO-1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1150 Anti-HLA-DQB1 (IIB3) h(41BB-CD3ζ) CAR, pCDCAR1 Human IIB3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1151 Anti-HLA-DQB1 (CBFYH-1360) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-1360 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1152 Anti-HLA-DQB1 (CBFYH-1361) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-1361 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1153 Anti-HLA-DQB1 (CBFYH-1362) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-1362 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1154 Anti-HLA-DQB1 (CBFYH-1363) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-1363 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1155 Anti-HLA-DQB1 (CBFYH-1364) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-1364 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY3935 Anti-HLA-DQB1 (SK10) h(CD28-CD3ζ) CAR, pCDCAR1 Human SK10 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4400 Anti-HLA-DQB1 (B-K27) h(CD28-CD3ζ) CAR, pCDCAR1 Human B-K27 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4401 Anti-HLA-DQB1 (BL-A/G3) h(CD28-CD3ζ) CAR, pCDCAR1 Human BL-A/G3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4402 Anti-HLA-DQB1 (ICO-1) h(CD28-CD3ζ) CAR, pCDCAR1 Human ICO-1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4403 Anti-HLA-DQB1 (IIB3) h(CD28-CD3ζ) CAR, pCDCAR1 Human IIB3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4404 Anti-HLA-DQB1 (CBFYH-1360) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-1360 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4405 Anti-HLA-DQB1 (CBFYH-1361) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-1361 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4406 Anti-HLA-DQB1 (CBFYH-1362) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-1362 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4407 Anti-HLA-DQB1 (CBFYH-1363) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-1363 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4408 Anti-HLA-DQB1 (CBFYH-1364) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-1364 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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