MAGE-A10

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.

Associated Disease
  • Melanoma

TCR Vector Products Product list:

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scFv-Host
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Vector
length
Vector
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Epitope Format HLA Data
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TCR-L057Z MAGE-A10 Human Human 8kb Lentiviral Non-modified HLA-A2 Inquiry
TCR-L058 MAGE-A10 Human Human 6700-8070bp retroviral vector Non-modified TCR HLA-A2 Inquiry

TCR Viral Particles Product list:

Catalog Target
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Packaging
System
Epitope Format Titer Data
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VP-TCR-C232 Human Human Lentivirus Non-modified TCR > 10⁷ IFU/ml Inquiry
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