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PDGFRA

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
  • AbTCR Vector Products

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    CAT Product Name Target Species Antibody Clone Fab-Host Animal Vector Type Targeting Cell Type Inquiry & Datasheet
    XS-0722-ZP3995 Anti-PDGFRA X CD3 BsAb Secreting T Cell Redirecting Vector (PDGFRAxCD3) Human T Cells   Add to Cart   Datasheet
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