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Peptide SIF

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Low avidity autoreactive T cells have been detected in several experimental setups and they can best be studied in transgenic systems expressing a model antigen as a neo self-antigen. Such a setup allowed us to directly compare the quality of antigenspecific T cells that can be found in the presence or the absence of the neo self-antigen. Rat insulin promoter (Rip)–mOva mice express a membrane-bound form of Ova in mTec in the thymus, the β cells in the islets of Langerhans in the pancreas, the proximal tubular epithelial cells in the kidneys, and, in the case of male mice, in the testis.
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CAT Product Name Target Species TCR Clone Host Species Epitope Allele Vector Type Inquiry & Datasheet
TCR-YC0958 Mouse anti-Peptide SIF T cell receptor (OT-III), pCDTCR1 OT-III Mouse SIFNFEKL H2-Kb Lentiviral vector   Add to Cart   Datasheet
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