All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
VivoCAR™ Anti-GD2 (KM666) h(CD28-41BB-CD3z) CAR circRNA leverages the robust KM666 chimeric ScFv to drive intense cytolytic activity against neuroectodermal tumors through in vivo T-cell reprogramming. The KM666 clone is significant for its high binding stability to the GD2 disialoganglioside, which is crucial for maintaining long-term immunological synapses in the dense tumor stroma. By utilizing the VivoCAR™ circRNA platform, the product achieves high-level, controlled CAR expression, providing a potent therapeutic pulse that can penetrate solid tumor masses while minimizing the neurotoxicity often associated with constitutive CAR expression.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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